Hemorrhage: EPL

ACOG recommended as an appropriate first-line therapy, unless contraindicated, as in patients with hypertension1,2

Bleeding due to early pregnancy loss (EPL) warrants expectant management to avoid complications3

Methergine and misoprostol are commonly used uterotonic medications for EPL hemorrhage*4

Little evidence exists to recommend starting with a particular agent5

Methergine Tablets have a rapid onset (5-10 minutes)6 and, unless contraindicated, are appropriate as a first-line agent to manage EPL hemorrhage2

*Due to uterine atony.
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PPH In The US Is Increasing | Know Postpartum Hemorrhage Risks

Ensure your patients are protected from Hospital to Home

  1. Practice Bulletin No. 76. American College of Obstetricians and Gynecologists. Obstet Gynecol. 2006;108(4):1039-1047.
  2. Second-trimester abortion. Practice Bulletin No.135. American College of Obstetricians and Gynecologists. Obstet Gynecol.2013;121:1394-1406.
  3. Weintraub AY, Sheiner E. Chapter2.Early pregnancy loss. Sheiner E(ed).Bleeding During Pregnancy: A Comprehensive Guide.2011.Springer Science+Business Media, LLC; Vol XI:25-44.
  4. O'Connell,Jones HE, Simon M, Saporta V, Paul M, Lichtenberg ES. First-trimester surgical abortion practices: a survey of National Abortion Federation members. Contraception.2009;79:385-392.
  5. Kerns J,Steinauer J, for the Society of Family Planning. Clinical guidelines: management of postabortion hemorrhage.Contraception.. 2013;87:331-342.
  6. Methergine® (methylergonovine maleate) 0.2 mg Tablets Prescribing Information.