Methergine®: The confidence of a generally well-tolerated safety profile1,2

Methergine IV has a comparable side effect profile to misoprostol capsules3,4

  • Methergine Tablets are contraindicated for patients with the following conditions: hypertension, toxemia, pregnancy, and hypersensitivity
  • Methergine-treated patients demonstrated a statistically significant lower incidence of shivering4 – Methergine 8.5% (8/94) vs misoprostol 42% (36/86) (P<0.0001)
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  1. Methergine® (methylergonovine maleate) 0.2 mg Tablets Prescribing Information.
  2. Dweck ME, Lynch CM, Spellacy WN. Use of methergine for the prevention of postoperative endometritis in non-elective cesarean section patients. Infect Dis Obstet Gynecol. 2000;8(3-4):151-154.
  3. Patil NB, Patted SS.A randomized controlled trial of oral misoprostol vs injection methylergometrine for prevention of post partum hemorrhage. Int J Reprod Contracept Obstet Gynecol. 2013;2:296-303.
  4. Amant F, Spitz B, Timmerman D, Corremans A, Van Assche FA. Misoprostol compared with methylergometrine for the prevention of postpartum haemorrhage: a double-blind randomized trial. Br J Obstet Gynecol. 1999;106:1066-1070.