Postpartum
Hemorrhage

Uterotonics: The standard of care1

PPH that requires blood transfusions due to uterine atony has more than doubled in the recent 10-year period.2

The incidence of PPH requiring blood transfusions more than doubled over the 10-year period from 2001-2002 to 2011-2012, which represents a statistically significant difference2:

– From 2.0 to 4.8 per 1000 (P<0.001)

Factors associated with increasing rates of PPH include1,3,4

  • Prolonged labor
  • Previous cesarean delivery
  • Advanced maternal age
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References
  1. Postpartum hemorrhage. Practice Bulletin No. 76. American College of Obstetricians and Gynecologists. Obstet Gynecol. 2006;108:1039-1047.
  2. Ahmadzia HK, Grotegut C, James A. Poster Session lll:509 - Rates of postpartum hemorrhage and related interventions: United States, 2000-2012. AJOG. 2016;214(1):S277.
  3. Anderson JM Etches D. Prevention and management of postpartum hemorrhage.Am Fam Physician.2007;75(6):875-882.
  4. Bateman BT, Tsen LC, Liu J, et al. Patterns of second-line uterotonic use in a large sample of hospitalizations for childbirth in the United States: 2007-2011. Anesth Analg. 2014;119:1344-1349.