Postpartum
Hemorrhage

Methergine Tablets demonstrate significant reduction in post-cesarean blood loss1

Methergine had less hemoglobin (Hb) loss1

Significantly higher postoperative Hb levels in those receiving Methergine (11.2 g/dL vs 10.2 g/dL, P <0.001)

- Methergine (-0.7 g/dL; -5.9%) vs no Methergine
(-1.6 g/dL; -12.7%)1
- 1 g/dL change in Hb (or 3% change in hematocrit) equates to one unit of blood2
- Reduced blood loss may reduce morbidity and speed recovery3-5

None of the Methergine-treated patients experienced any side effects leading to withdrawal from the study1

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References
  1. Dweck MF,Lynch CM,Spellacy WN.Use of methergine for the prevention of postoperative endometritis in non-elective cesarean section patients.Infects Dis Obstet Gynecol.2000;8(3-4):151-154.
  2. Elzik ME,Dirschl DR,Dahners LE.Correlation of transfusion volume to change in hematocrit.Am J Hematol. Feb;81(2):145-146.
  3. Oyelese Y,Ananth CV.Postpartum hemorrhage:epidemiology,risk factors,and causes.Clin Obstet Gynecol.;53:147-156.
  4. Lourens R,Paterson-Brown S.Ergometrine given during caesarean section and incidence of delayed postpartum haemorrhage due to uterine atony. J Obstet Gynaecol. 2007;27:795-797.
  5. Healthline Networks Inc. Labor & delivery: complications of cesarean section. Available at: http://www.healthline.com/health/pregnancy/ complications-cesarean-section. Accessed February 26, 2016.